Agenzia Italiana del Farmaco
Direct communication with healthcare professionals on etoposide-containing medicinal products - Direct communication with healthcare professionals on etoposide-containing medicinal products
Direct communication with healthcare professionals on etoposide-containing medicinal products
Etoposide: Risk of infusion-related hypersensitivity reactions when administered with an in-line filter.
Summary
The following recommendations apply only to etoposide and not to etoposide phosphate:
- An increased risk of infusion-related hypersensitivity reactions has been observed with the use of in-line filters during administration of etoposide-containing medicinal products.
- It is currently unknown whether the risk increase occurs with all types of in-line filters or only with in-line filters made of certain materials.
- In-line filters should not be used.
Published on: 04 March 2024